Table 2. Univariate and multifactorial Cox regression analyses of the effect of CSPG4 and pathological parameters on the prognosis in patients with BLCA.

Characteristics	Total (N)	Univariate analysis			Multivariate analysis
		Hazard ratio (95% CI)	P-value		Hazard ratio (95% CI)	P-value
Age	55		0.751
>65	37	Reference
≤65	18	1.128 (0.539 - 2.358)	0.749
Gender	55		0.512
male	46	Reference
female	9	1.362 (0.556 - 3.333)	0.499
Tumor size	55		0.151
>3cm	23	Reference
≤3cm	32	1.715 (0.809 - 3.634)	0.160
Tumor stage	55		0.021
>T2	27	Reference			Reference
≤T2	28	0.430 (0.207 - 0.890)	0.023		0.587 (0.262 - 1.314)	0.195
Tumor grade	55		0.562
high	48	Reference
low	7	0.713 (0.216 - 2.356)	0.579
Vascular invasion	55		0.164
Yes	22	Reference
No	33	1.692 (0.792 - 3.617)	0.175
Lymph node metastasis	55		0.091
Yes	12	Reference			Reference
No	43	0.489 (0.223 - 1.075)	0.075		0.469 (0.210 - 1.045)	0.064
CSPG4	55		0.001
Yes	28	Reference			Reference
No	27	0.298 (0.139 - 0.639)	0.002		0.384 (0.167 - 0.882)	0.024