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. 2023 Dec 11;14(12):815. doi: 10.1038/s41419-023-06352-4

Fig. 1. Mint3 depletion does not affect chemoresistance in vitro in TNBC cell lines.

Fig. 1

A, B Expression of Mint3 in MDA-MB-231 (A) and MDA-MB-468 cells (B) expressing doxycycline-inducible shRNAs against Mint3 (ishMint3) treated with doxycycline (1 μg/ml) for 3 days. C, D Cytotoxicity assay of control (DOX(−)) and doxycycline-pre-treated (DOX (+)) MDA-MB-231 (C) and MDA-MB-468 (D) ishMint3 cells in the presence of doxorubicin (DXR) for 24 h at the indicated concentration. E, F Cytotoxicity assay of control (DOX(−)) and doxycycline-pre-treated (DOX(+)) MDA-MB-231 (E) and MDA-MB-468 (F) ishMint3 cells in the presence of paclitaxel (PTX) for 24 h at the indicated concentration. In CF, the data represent the mean ± SD (n = 3).