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. 2023 Dec 11;13:21909. doi: 10.1038/s41598-023-49405-6

Table 1.

Univariate analysis of patient demographic data, preoperative risk factors and surgical data.

GIB (n = 52) non-GIB (n = 180) P t/χ2
Age (years) 63.87 ± 8.49 60.20 ± 9.44 0.012 2.52
Age ≥ 65 years 26 (50.0) 67 (37.2) 0.032 4.61
Sex (Male) 46 (88.5) 145 (80.6) 0.188 1.73
EF (%) 60.87 ± 9.20 54.02 ± 14.08  < 0.001 4.15
NYHA ≥ 3 39 (75.0) 120 (66.7) 0.254 1.30
Cerebral infarction 9 (17.3) 18 (10.0) 0.148 2.10
Hypertension 34 (65.4) 105 (58.3) 0.361 0.84
Diabetes 21 (40.4) 67 (37.2) 0.679 0.17
Digestive tract diseases 8 (15.4) 20 (11.1) 0.405 0.69
Smoke 39 (75.0) 114 (63.3) 0.118 2.45
MI 12 (23.1) 43 (23.9) 0.903 0.02
Number of diseased vessels 3.37 ± 0.74 3.12 ± 0.90 0.075 1.79
PPI use 8 (15.4) 32 (17.8) 0.687 0.16
Aggrastat use 27 (51.9) 123 (68.3) 0.029 4.75
LMWHC use 18 (34.6) 33 (18.3) 0.013 6.24
Blood platelet 198.06 ± 60.98 198.83 ± 62.76 0.938 0.08
INR 1.02 ± 0.10 1.02 ± 0.07 0.885 0.15
ALT 32.09 ± 44.59 34.80 ± 27.14 0.591 0.54
AST 27.65 ± 30.63 28.13 ± 34.01 0.927 0.09
GGT 39.42 ± 33.97 40.63 ± 33.89 0.821 0.23
Total bilirubin 17.98 ± 6.52 15.27 ± 10.32 0.392 0.86
Albumin 41.47 ± 5.55 44.16 ± 4.40  < 0.001 3.65
Prealbumin 245.23 ± 59.72 255.57 ± 57.69 0.260 1.13
Urea 7.37 ± 2.84 6.09 ± 2.31  < 0.001 3.33
Creatinine 95.60 ± 38.97 83.19 ± 26.69 0.009 2.64
GFR 76.33 ± 21.26 84.77 ± 18.88 0.006 2.76
Uric Acid 285.68 ± 110.40 361.82 ± 97.96 0.134 1.51
CPB use 38 (73.1) 78 (43.3)  < 0.001 14.28
CPB time 121.79 ± 90.52 67.96 ± 95.19  < 0.001 3.63
ACCT 64.00 ± 54.84 31.59 ± 56.64  < 0.001 3.66
Intraoperative transfusion 38 (73.1) 83 (46.1)  < 0.001 11.76
Time of operation 382.67 ± 93.27 339.29 ± 100.15 0.006 2.79
Mechanical ventilation time 7660.52 ± 8456.67 2377.25 ± 4780.31  < 0.001 5.79
ICU stay time 8.79 ± 8.10 3.3 ± 1.75  < 0.001 8.42
IABP use 16 (30.8) 31 (17.2) 0.032 4.58
Re-operation for bleeding 11 (21.2) 6 (3.3)  < 0.001 18.87
Arrhythmia 28 (53.8) 35 (19.4)  < 0.001 24.14
Low cardiac output syndrome 16 (30.8) 32 (17.8) 0.042 4.15
Infection 30 (57.7) 39 (21.7)  < 0.001 25.06

The results were expressed as mean ± standard deviation or n (%).

EF left ventricular ejection fraction, MI myocardial infarction, PPI proton pump preparation, INR international normalized ratio, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT gamma-glutamyltransferase, GFR glomerular filtration rate, CPB cardiopulmonary bypass, ACCT aorticcross-clamptime, ICU intensive care unit, IABP intra-aortic ballon pump, LMWHC low molecular-weight heparin calcium.