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. 2023 Dec 11;14:8207. doi: 10.1038/s41467-023-44040-1

Fig. 2. Loss of IL31RA has no effect on house dust mite (HDM)-induced airway inflammation and goblet cell hyperplasia.

Fig. 2

a Representative image of hematoxylin and eosin-stained lung sections from wildtype (n = 5) and IL-31RA–/– (n = 5) mice treated with saline or HDM. Images were taken at ×20 magnification, scale bar 100 µm. b, c Total bronchoalveolar lavage (BAL) cell number and the differential cell count of BAL cells of wild-type and IL-31RA-/- mice treated with saline (n = 5) or HDM (n = 5). Eos, eosinophils; Mac, macrophages; Lym, lymphocytes; and Neu, neutrophils. One-way ANOVA was used. d Representative images of Alcian blue periodic acid-Schiff (ABPAS) staining of lung sections from wildtype (n = 7) and IL-31RA–/– (n = 7) mice treated with saline or HDM. Images were taken at ×20 magnification, scale bar 100 µm. e The percent of ABPAS-positive cells normalized to total cell in the airways of wild-type and IL-31RA–/– mice treated with saline (n = 7) or HDM (n = 7). Data are shown as mean ±SEM. One-way ANOVA was used. At least two independent experiments produced similar results. Source data are provided as a Source Data file.