TABLE 2.
Details of mutant genes.
| Genes | Chr | Mutations | Type | Variant allele frequencies (%) | CGC cancer types |
|---|---|---|---|---|---|
| BRCA1 | 17 | NM_007297:exon9:c.G3702C:p.Q1234H | Non-synonymous SNV | 16.1 | Ovarian (somatic) |
| BLM | 15 | NM_000057:exon16:c.A3167G:p.K1056R | Non-synonymous SNV | 39.5 | Leukemia, lymphoma, skin squamous carcinoma, other tumor types (germline) |
| FOXA1 | 14 | NM_004496:exon2:c.754_774del:p.252_258del | Non-frameshift deletion | 17.3 | breast, prostate (somatic) |
| SETX | 9 | NM_001351527:exon10:c.4301_4310del:p.D1434fs | Frameshift deletion | 26.7 | Undertermined |