Table 2.
Logistic regression for factors impacting MIS
| Exposure | Open (%) n = 52,098 |
MIS (%) n = 41,637 |
Univariate OR (95% CI) |
Multivariate OR (95% CI) |
|---|---|---|---|---|
| Gender | ||||
| Male | 27,198 (52.21) | 20,722 (49.77) | 1.00a | 1.00a |
| Female | 24,900 (47.79) | 20,915 (50.23) | 1.10 (1.07–1.13) | 1.15 (1.12–1.19) |
| Age (per year) | 0.99 (0.99–0.99) | 0.99 (0.99–0.99) | ||
| Charlson score | ||||
| 0 | 8987 (17.25) | 7963 (19.12) | 1.00a | 1.00a |
| 1 | 4003 (7.68) | 3064 (7.36) | 0.86 (0.82–0.91) | 0.80 (0.75–0.85) |
| 2+ | 39,108 (75.07) | 30,610 (73.52) | 0.88 (0.85–0.91) | 0.73 (0.70–0.76) |
| Ethnicity | ||||
| White | 48,498 (93.09) | 37,808 (90.80) | 1.00a | 1.00a |
| Asian | 1228 (2.36) | 1302 (3.13) | 1.36 (1.26–1.47) | 1.16 (1.06–1.26) |
| Black | 1007 (1.93) | 859 (2.06) | 1.09 (1.00–1.20) | 0.97 (0.87–1.07) |
| Other/Mixed | 1365 (2.62) | 1668 (4.01) | 1.57 (1.46–1.69) | 1.10 (1.01–1.19) |
| IMD* | ||||
| 1 | 11,526 (22.15) | 10,312 (24.80) | 1.00a | 1.00a |
| 2 | 11,206 (21.54) | 9220 (22.17) | 0.92 (0.89–0.96) | 0.97 (0.93–1.01) |
| 3 | 10,686 (20.54) | 8419 (20.24) | 0.88 (0.85–0.92) | 0.94 (0.90–0.98) |
| 4 | 9866 (18.96) | 7569 (18.20) | 0.86 (0.82–0.89) | 0.90 (0.86–0.94) |
| 5 | 8750 (16.82) | 6068 (14.57) | 0.78 (0.74–0.81) | 0.85 (0.81–0.89) |
| Indication | ||||
| Cancer | 33,489 (64.28) | 29,449 (70.73) | 1.00a | 1.00a |
| IBD | 4400 (8.45) | 3704 (8.90) | 0.96 (0.91–1.00) | 0.61 (0.57–0.64) |
| Diverticular disease | 5045 (9.68) | 2717 (6.53) | 0.61 (0.58–0.64) | 0.49 (0.46–0.51) |
| Other | 9164 (17.59) | 5767 (13.85) | 0.72 (0.69–0.74) | 0.47 (0.45–0.49) |
| Increasing year | 1.19 (1.18–1.19) | 1.19 (1.19–1.20) | ||
| Region | ||||
| West Midlands | 9458 (18.2) | 6929 (16.6) | 1.00a | 1.00a |
| North East | 1993 (3.8) | 1666 (4.0) | 1.14 (1.06–1.23) | 1.23 (1.14–1.33) |
| North West | 9902 (19.0) | 5630 (13.5) | 0.78 (0.74–0.81) | 0.75 (0.72–0.79) |
| Yorkshire & Humber | 2182 (4.2) | 1404 (3.4) | 0.88 (0.82–0.95) | 0.87 (0.80–0.94) |
| East Midlands | 1304 (2.5) | 838 (2.0) | 0.88 (0.80–0.96) | 0.83 (0.75–0.91) |
| East of England | 2214 (4.3) | 2111 (5.1) | 1.30 (1.22–1.39) | 1.34 (1.25–1.44) |
| South West | 7086 (13.6) | 5840 (14.0) | 1.12 (1.07–1.18) | 1.16 (1.10–1.22) |
| South Central | 5240 (10.1) | 6786 (16.3) | 1.77 (1.69–1.85) | 1.77 (1.68–1.86) |
| London | 7692 (14.8) | 6585 (15.8) | 1.17 (1.12–1.22) | 1.11 (1.05–1.16) |
| South East Coast | 5018 (9.6) | 3843 (9.2) | 1.05 (0.99–1.10) | 1.04 (0.98–1.10) |
All categories p < 0.001
*Index of multiple deprivation, ordered by increasing deprivation
aReference groups presented with OR of 1