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. 2023 Nov 28;14:1277017. doi: 10.3389/fimmu.2023.1277017

Table 4.

Summary of risk factors for IgAN recurrence.

Risk factors Protective factors
Young recipient HLA-B46 antigen
Young donor Induction with anti-IL-2-R antibodies
Rapid progression from IgAN diagnosis to ESKD MMF
Short time on dialysis Pretransplant tonsillectomy
Low total HLA mismatches
Low HLA-DR mismatches
Male recipient
Related donor
Retransplantation
Hemodialysis
No induction therapy
mTOR inhibitor
ACEI/ARB

IgAN, immunoglobulin A nephropathy; ESRD, end stage renal disease; HLA, human leukocyte antigen; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blockers; MMF, mycophenolate mofetil.