Table 1.
Chance node | Absolute annual risk, % (95% CI) |
---|---|
Risk of having a thromboembolic event (stroke) among patients with untreated atrial fibrillation1,11,12,13 | |
Age 65-75 yr | |
No risk factor | 4.3 (2.7-7.1) |
≥1 risk factor | 5.7 (3.9-8.3) |
Congestive cardiac failure, no risk factor | 8.4 (2.1-33.0) |
Congestive cardiac failure, ≥1 risk factor | 11.7 (5.3-26.0) |
Age > 75 yr | |
No risk factor | 3.5 (3.5-26.0) |
≥1 risk factor | 8.1 (4.7-13.9) |
Congestive cardiac failure, no risk factor | 10.9 (1.4-78.0) |
Congestive cardiac failure, ≥1 risk factor | 19.7 (7.4-52.0) |
Previous cardiovascular accident or TIA | 12.0‡ |
Relative risk reduction when treated with warfarin sodium1 | |
Annual risk reduction, % | 68 |
Probability of outcome after thromboembolic event (stroke)14 | |
Affected (functionally dependent) | 35 (30.0-39.0) |
Unaffected (functionally independent) | 65 (61.0-70.0) |
Probability of side effects with warfarin treatment15 | |
Minor side effect | 11.8 (8.8-16.0) |
Major side effect | 1.1 (0.5-1.5) |
Any side effect | 12.9‡ |
Risk factor = diabetes mellitus or hypertension (but not congestive cardiac failure). | |
CI = confidence interval; TIA = transient ischemic attack. |