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Release of inflammatory mediators in MDM. Cells were treated with Css-CRiSP (1 μM) or LPS (0.25 μg/mL). At different time points, supernatants were collected and IL-6 (A), IL-8 (B), IL-1β (C), TNF-α (D), and IL-10 (E) were determined by ELISA. Results represent 3 independent experiments in duplicate (mean ± SD). *p < 0.05 vs. negative control. Negative control: cells treated with PBS. Positive control: cells treated with LPS.
