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. 2023 Sep 15;38(16):3451–3459. doi: 10.1007/s11606-023-08347-5

Table 2.

Calibration for QFracture and FRAX MOF and Hip Fracture Prediction by Risk Quantile

QFracture FRAX
Quantile Number of people Fracture Rate (%) Mean Predicted Risk (%) Observed to Predicted Ratio Number of people Fracture Rate (%) Mean Predicted Risk (%) Observed to Predicted Ratio
MOF 1 2419 0.25 0.07 3.5 2421 0.21 0.26 0.8
2 2419 0.58 0.15 3.9 2418 0.62 0.51 1.2
3 2419 0.83 0.23 3.6 2430 0.74 0.74 1.0
4 2419 1.32 0.32 4.1 2411 1.37 0.98 1.4
5 2419 1.28 0.43 3.0 2416 1.49 1.27 1.2
6 2419 1.94 0.58 3.3 2421 1.94 1.61 1.2
7 2419 2.03 0.80 2.5 2418 2.48 2.03 1.2
8 2419 2.89 1.13 2.6 2419 2.56 2.58 1.0
9 2419 2.77 1.75 1.6 2417 3.23 3.47 0.9
10 2418 5.54 4.17 1.3 2418 4.80 6.56 0.7
Hip Fracture 1 4838 0.02 0.009 2.3 4896 0.04 0.02 1.8
2 4838 0.06 0.03 1.8 4942 0.08 0.07 1.2
3 4838 0.13 0.09 1.7 4694 0.13 0.15 0.9
4 4838 0.33 0.22 1.5 4840 0.33 0.35 0.9
5 4837 0.75 1.34 0.6 4817 0.79 1.67 0.5

MOF, Major osteoporotic fracture

Quantile 1 is the group with the lowest predicted fracture risk, and increasing quantiles represent increasing predicted fracture risk.