FIGURE 7.

Expression of p53 was suppressed by folic acid (FA), which is related to the expression of α‐syn in patient‐derived dopaminergic neurons (MD‐DNs). (A) Dental pulp stem cells were differentiated into DNs in the absence or presence of FA. p53 expression was measured by quantitative reverse transcription polymerase chain reaction (qRT‐PCR). The mean ± standard error of the mean (SEM) was obtained from four independent experiments. n.s., not significant. (B) Dental pulp stem cells were transfected with negative control‐ and p53‐siRNA (p53‐siR) and differentiated into DNs. p53 and α‐syn expression was measured by qRT‐PCR. The mean ± standard error of the mean (SEM) was obtained from four independent experiments. n.s., not significant.