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. 2001 Jun;174(6):415–420. doi: 10.1136/ewjm.174.6.415

Table 1.

Treatment of asthma in adults and children older than 5 years*

Step Long-term control Quick relief
Step 4: Severe persistent
  1. Anti-inflammatory drug: inhaled corticosteroid (high dose) and

  2. Long-acting bronchodilator: salmeterol xinafoate, theophylline, or long-acting bronchodilator tablets and

  3. Oral corticosteroids, 2 mg/kg/d

Short-acting bronchodilator: inhaled β2-agonists as needed
Step 3: Moderate persistent
  1. Anti-inflammatory drug: inhaled corticosteroid (medium dose) or

  2. Inhaled corticosteroid (low to medium dose) plus salmeterol, theophylline, or long-acting β2-agonist tablets

Short-acting bronchodilator: inhaled β2-agonists as needed. If using >2 × /wk, consider increasing to the next step
Step 2: Mild persistent
  1. Anti-inflammatory drug: inhaled corticosteroids (low dose) or mast cell stabilizer

  2. Theophylline and leukotriene inhibitors are alternatives

Short-acting bronchodilator: inhaled β2-agonists as needed. If using >2 × /wk, consider increasing to the next step
Step 1: Mild intermittent No daily medication Short-acting bronchodilator: inhaled β2-agonists as needed. If using >2 × /wk, consider increasing to the next step
*

From the National Asthma Education and Prevention Program.3