Table 2. Activities against an Extended Panel of MDR Bacteria.

	MICa
Cpd	P. aeruginosa PA14	PA14 4.13 (phoQ)	PA14 4.18 (pmrB)	PA14 2P4 (pmrB)	ZEM-1A	ZEM9A	E. cloacae	K. pneumoniae OXA-48	S. maltophilia	B. cenocepacia	S. aureus Newman	S. epidermis
PMB	<0.13	0.25	1	1	<0.13	2	0.5–1	1–2	0.5	>16	>16	>16
ln65	2–4	4	32	32	2	4	2	2	2	>32	2	2
ln69	2	4	16	32	2	4–8	4	4	2	>32	8	2–4
EB1	4	8	32	32	2–4	16	8	8–16	2–4	>32	32	4–8
EB5	4–8	8	32	>32	2	8	8–16	32–64	8	>32	>32	4–8
EB6	2–4	4	16	32	2	4	4	8	2–4	>32	8	2–4
Oncb	2	2	2	2	2	16	2	1	>32	32	1	4
EB9b	2	2	4–8	4	2–4	2	16	32	8	>32	4	2
EB11b	2–4	4–8	8–16	8–16	2–4	4	16	32	4	>32	4	1

^aMinimum inhibitory concentrations (in μg/mL) were determined in Mueller–Hinton broth (MH) at pH 7.4 after incubation for 16–20 h at 37 °C. Values represent two different duplicate MIC determinations.

^bMIC values were determined in diluted MH (12.5% MH) at pH 8.5 for Onc, EB9, and EB11. ZEM-1A and ZEM9A are two clinical MDR P. aeruginosa isolates.