TABLE 1.
Cefiderocol susceptibility by broth microdilution and disk diffusion and by population analysis profiling of 38 baseline carbapenem-resistant Acinetobacter calcoaceticus-baumannii complex isolates in the cefiderocol arm in the CREDIBLE-CR study a
| BMD phenotype | Disk diffusion phenotype | PAP phenotype at 72-hour time point | |||
|---|---|---|---|---|---|
| S (inhibition zone ≥ 15 mm) n (row %) | Non-S (inhibition zone < 15 mm) n (row %) | S n (row %) |
HR n (row %) |
R n (row %) |
|
| S (MIC ≤ 4 µg/mL; n = 36) | 35 (97.2) | 1 (2.8) | 7 (19.4) | 18 (50.0) | 11 (30.6) |
| I (MIC = 8 µg/mL; n = 1) | 1 (100) | 0 | 0 | 0 | 1 (100) |
| R (MIC ≥ 16 µg/mL; n = 1) | 0 | 1 (100) | 0 | 0 | 1 (100) |
| Total (N = 38) | 36 (94.7) | 2 (5.3) | 7 (18.4) | 18 (47.4) | 13 (34.2) |
a
n, number of isolates in the category.