TABLE 5.
Distribution of beta-lactamases in 38 carbapenem-resistant Acinetobacter calcoaceticus-baumannii complex isolates by population analysis profiling phenotype in the cefiderocol arm in the CREDIBLE-CR study a
| Beta-lactamase enzyme b | Overall (n) | PAP-S (n) | PAP-HR (n) | PAP-R (n) |
|---|---|---|---|---|
| OXA-23 | 20 | 4 | 11 | 5 |
| OXA-24 | 2 | 0 | 1 | 1 |
| OXA-72 | 2 | 1 | 0 | 1 |
| TEM-1, OXA-23 | 9 | 2 | 3 | 4 |
| TEM-1, OXA-24 | 1 | 0 | 1 | 0 |
| TEM-1, OXA-72 | 0 | 0 | 0 | 0 |
| TEM-1, NDM-1 | 1 | 0 | 0 | 1 |
| TEM-OSBL; OXA-23 | 1 | 0 | 1 | 0 |
| TEM-1; NDM-1; OXA-23 | 1 | 0 | 1 | 0 |
| No acquired beta-lactamase detected | 1 | 0 | 0 | 1 |
| Total | 38 | 7 | 18 | 13 |
a
n, number of isolates with beta-lactamase enzymes.
b
OSBL, original-spectrum beta-lactamase; OXA, oxacillinase.