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. Author manuscript; available in PMC: 2023 Dec 12.
Published in final edited form as: Nat Genet. 2023 Jul 10;55(8):1370–1380. doi: 10.1038/s41588-023-01442-7

Extended Data Figure 2. Matching possible confounders between CRISPRi functional and nonfunctional pairs.

Extended Data Figure 2.

Histograms demonstrating the distribution of functional and high-confidence nonfunctional enhancer-promoter pairs in terms of enhancer-promoter genomic distance (top), accessibility by mean ATAC-seq signal (middle) and PRO-seq target gene transcription signal in reads per kilobase per million reads (RPKM) (bottom), after matching for these possible confounding factors.