Fig 7.

Comparison of protein expression of molecules related to activation of the MAPK pathway and inflammatory response in the lungs of mice after challenge with T. pyogenes. Representative western blots show the expression and phosphorylation level of (A) JNK, (B) ERK, (C) p38, (D) AKT, and (E) NF-κB. Densitometry analysis from three independent experiments was used to quantitate the protein expression, and the ratio of phosphorylated protein to total protein presented the relative expression results, and the values were normalized to the control value (relative density ratio). The mean ± SD of three experiments are shown; *P < 0.05, **P < 0.01, and ***P < 0.001.