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. 2023 Nov 1;11(6):e00865-23. doi: 10.1128/spectrum.00865-23

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Copyright © 2023 Petersen et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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Fig 3 — Antibody levels and IFN-γ levels dynamics over time in convalescent individuals using mixed models. Distribution of (A) serum IgG levels, represented in log10(AU/mL), (B) saliva IgG levels, represented in log10(FI), (C) NAbs levels, represented in log10(IU/mL); and (D) IFN-γ levels, represented in log10(mIU/mL) over time (days from positive RT-PCR result). Circles represent observed levels for (A) serum IgG, (B) saliva IgG, (C) NAbs, and (D) IFN-γ. Solid lines represent predicted levels for (A) serum IgG levels, (B) saliva IgG levels, (C) NAbs levels, and (D) IFN-γ levels. Black, yellow, and blue colors represent unvaccinated convalescent individuals (group 2), vaccinated convalescent individuals (second dose; group 5), and vaccinated convalescent individuals (third dose; group 6), respectively. The horizontal dotted line represents the assay positivity threshold. The confidence interval (95%) is represented by the shadowed areas. The center for the confidence interval is the predicted (mean) values.