Fig 1.

Effects of fluvastatin treatment on intracellular cholesterol levels, Wolbachia loads, and ZikV titers in C6/36 cells (4 days post-infection). (A) Intracellular cholesterol detected per 10,000 cells quantified by enzymatic cholesterol assay (Promega). (B) Wolbachia loads per C6/36 cell were measured via qPCR. (C) ZikV titers determined via plaque assay from supernatant collected from cultures at day 6 post-infection. Blue bars represent W− C6/36 cells while red bars represent W+ C6/36 cells.