TABLE 1.
Antibiotics | M. abscessus strains/MICs (μg/mL) | |||||
---|---|---|---|---|---|---|
QRDRWT | QRDRGyrAA17S | QRDRGyrAA17S17A | QRDRGyrAA17G+T7A | QRDRGyrAA17G | QRDRGyrAT7A | |
Levofloxacin | 16 | 4 | 16 | 4 | 4 | 16 |
Moxifloxacin | 8 | 2 | 8 | 4 | 4 | 8 |
Rifabutin | 4 | 4 | 4 | 4 | 4 | 4 |
Amikacin | 4 | 4 | 4 | 4 | 4 | 4 |
Broth microdilution method was used to determine the MICs. The MIC was defined as the lowest drug concentration that prevented visible bacterial growth. The experiment was performed in triplicate and repeated twice.