Fig 2.

Log₂ transformed bla copy number variant (CNV) estimates for BL/BLI isolates with a single exogenous β-lactamase gene after excluding isolates with non-exogenous BL/BLI genetic determinant factors. (A) CNV estimates for bla _TEM-1 for 91 E. coli isolates stratified by BL/BLI group indicated by shape. Horizontal dashed line indicates cut-off for 2× CNV; (B) bla _TEM-1 CNV across each of the BL/BLI groups; (C) bla _TEM-1 CNV by SAM MIC; (D) bla _TEM-1 CNV by AMC MIC; (E) bla _TEM-1 CNV by TZP MIC; (F) bla _OXA-1 CNV by TZP MIC. Global P-values for Kruskal-Wallis or Wilcoxon rank-sum tests are reported above each respective panel. For global P-value <0.05, pairwise Wilcoxon rank-sum test adjusted P-values are reported as follows: *P < 0.05, **P < 0.01, ***P < 0.001.