Table 1. Results of the Mann-Kendall Test for Trend for 48 time-series observations by pathogen and initial inoculum level.

				Mann-Kendall Test Values
Pathogen	Lot	Replicate	n	S	p-value	conclusion
Campylobacter (43 to 162 CFU/mL initial inoculum)	A	1	6	-10	0.035	↘
		2	6	-12	0.013	↘
	B	1	6	-12	0.013	↘
		2	6	-9	0.036	↘
	C	1	6	-10	0.035	↘
		2	6	-12	0.013	↘
Campylobacter (600 to 1,100 CFU/mL initial inoculum)	A	1	6	-12	0.013	↘
		2	6	-12	0.013	↘
	B	1	6	-12	0.018	↘
		2	6	-8	0.090	NT
	C	1	6	-12	0.018	↘
		2	6	-14	0.006	↘
L. monocytogenes (26 to 41 CFU/mL initial inoculum)	A	1	6	11	0.030	+
		2	6	10	0.043	+
	B	1	6	11	0.030	+
		2	6	11	0.030	+
	C	1	6	9	0.066	NT
		2	6	9	0.066	NT
L. monocytogenes (3,000 to 7,900 CFU/mL initial inoculum)	A	1	6	13	0.012	+
		2	6	9	0.066	NT
	B	1	6	13	0.012	+
		2	6	15	0.004	+
	C	1	6	13	0.012	+
		2	6	9	0.066	NT
E. coli O157:H7 (22 to 46 CFU/mL initial inoculum)	A	1	6	-3	0.354	NT
		2	6	-1	0.500	NT
	B	1	6	-3	0.354	NT
		2	6	-3	0.354	NT
	C	1	6	-8	0.090	NT
		2	6	-4	0.283	NT
E. coli O157:H7 (6,700 to 8,300 CFU/mL initial inoculum)	A	1	6	-7	0.130	NT
		2	6	-5	0.226	NT
	B	1	6	-5	0.226	NT
		2	6	-1	0.500	NT
	C	1	6	-9	0.066	NT
		2	6	-3	0.354	NT
Salmonella (56 to 86 CFU/mL initial inoculum)	A	1	6	9	0.066	NT
		2	6	-3	0.354	NT
	B	1	6	-9	0.066	NT
		2	6	1	0.500	NT
	C	1	6	-11	0.030	↘
		2	6	-12	0.018	↘
Salmonella (3,700 to 6,200 CFU/mL initial inoculum)	A	1	6	-11	0.030	↘
		2	6	-7	0.130	NT
	B	1	6	-12	0.018	↘
		2	6	-15	0.004	↘
	C	1	6	-9	0.066	NT
		2	6	-15	0.004	↘

Notes: Lot = bottle of raw milk; A, B, and C were bottles from the same day of production; Replicate = duplicate analyses from each lot of raw milk; n = number of observations in each time series; S = Mann-Kendall test statistic; p-values less than 0.05 shown in bold font indicating a statistically significant increasing or decreasing trend conclusion; Down arrows = Evidence of a statistically significant decreasing trend; + = Evidence of a statistically significant increasing trend; NT = no trend observed.