Table 4. Known SNP associations overlapping significant haplotypes for worm burden.

A: Significant haplotypes overlapping published SNPs
Locus	N	SNP identifier of published associations		Gene	OR(CI)			P	Freq(%)
Chr12: 57510661–57525756	8	rs324013		STAT6	5.7(1.24–26.26)			0.03	1.35
Chr1:206940831–206947167	106	rs3024495, rs1800871, rs1800872, rs1800896		IL10	0.53(0.32–0.88)			0.02	17.85
B: Current study effect of haplotypes rs1800871 and rs1800896
			OR (CI)			p-value	Freq (%)
		AT	0.82(0.47–1.42)			0.476	11
		GT	1.10(0.70–1.74)			0.677	16
		AC	Reference			NA	62
		GC	0.52 (0.28–0.97)			0.039	8

Part A: Known SNPs associations refers to the column “SNP identifier of published associations”. These are contained within the loci named in column “Locus”. The OR(CI), P and Freq(%) are for the haplotype loci. OR(CI) = Odds ratio (95% confidence interval); P = p-value; Freq(%) = Frequency(percentage).

N is number of chromosomes included in the analysis, see N in S5 Table. The Bonferroni threshold was 0.00015 (0.05/332 haplotype blocks listed in S1 Appendix).