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. 2023 Nov 30;17(11):e0011796. doi: 10.1371/journal.pntd.0011796

Table 5. Expression quantitative trait loci (eQTL) associated with worm burden.

A) 100kb analysis: Flanking regions of 100 kilobases on either side of candidate gene
GENE N Chr Significant SNP identifier BP Raw P Bonferroni Adjusted P
IL5 101 5 rs201918473 131,821,658 8.02E-05 0.0081
IL5 101 5 kgp11181534 131,822,055 8.02E-05 0.0081
IL5 101 5 kgp7862224 131,822,072 8.02E-05 0.0081
IL5 101 5 kgp6078763 131,819,126 0.00010 0.010
IL5 101 5 rs13165038 131,813,350 0.00010 0.011
IL6 152 7 rs114644824 22,867,134 0.00025 0.038
IL5 101 5 kgp2459073 131,813,219 0.00049 0.049
IL5 101 5 kgp888688 131,819,921 0.00049 0.049
B) 1Mb analysis: Flanking regions of 1 megabase on either side of candidate gene
GENE N Chr Significant SNP identifier BP Raw P Bonferroni Adjusted P
IL25 1262 14 h3a_37_14_24685193_T_C 24,685,193 1.30E-05 0.016
IFNG 1353 12 kgp3424793 69,349,042 1.63E-05 0.022
IL21 954 4 kgp10917231 123,831,293 3.74E-05 0.036
IL21 954 4 rs13106595 123,873,534 3.74E-05 0.036
IL5 997 5 rs201918473 131,821,658 8.02E-05 0.080
IL5 997 5 kgp11181534 131,822,055 8.02E-05 0.080
IL5 997 5 kgp7862224 131,822,072 8.02E-05 0.080

N = number of SNP tested for association with gene RNA sequences

The number of individuals who had data analyzed were 38 infected and 20 uninfected children.

SigSNP = Significant SNP

Raw P = Raw p-value

Bonferroni adjusted P = p-values adjusted by Bonferroni correction (Raw P * N)