Table 4.
Decreased Brain Activation with Traumatic Scripts in Traumatized Non-PTSD Women
Brain areas with significant (p < 0.005) deactivations during exposure to personalized trauma scripts in participants with posttraumatic stress disorder as measured with high-resolution positron emission tomography. Significant clusters are presented by size (number of voxels) and location (Brodmann area, cluster peak Talairach coordinates). Sub-cluster peaks are also identified.
Voxel Number |
Brain Region | Brodmann Area |
X | Y | Z | Z Score |
---|---|---|---|---|---|---|
470 | L. Middle Frontal Gyrus | 6 | −20 | 12 | 62 | 5.58 |
L. Superior Frontal Gyrus | 6 | −22 | 2 | 70 | 4.38 | |
L. Middle Frontal Gyrus | 6 | −34 | 6 | 62 | 4.01 | |
1200 | R. Supramarginal Gyrus | 40 | 56 | −48 | 32 | 5.15 |
R. Inferior Parietal Lobule | 7 | 36 | −58 | 48 | 4.92 | |
R. Inferior Parietal Lobule | 40 | 42 | −42 | 44 | 4.69 | |
1121 | R. Cerebellar Tonsil | 42 | −54 | −44 | 4.99 | |
R. Inferior Temporal Gyrus | 20 | 62 | −52 | −16 | 4.88 | |
R. Cerebellar Tonsil | 46 | −52 | −34 | 4.69 | ||
633 | R. Middle Frontal Gyrus | 46 | 56 | 32 | 22 | 4.84 |
R. Middle Frontal Gyrus | 9 | 48 | 6 | 36 | 4.77 | |
R. Middle Frontal Gyrus | 9 | 52 | 22 | 28 | 4.41 | |
658 | L. Superior Frontal Gyrus | 10 | −32 | 56 | 24 | 4.75 |
L. Middle Frontal Gyrus | 9 | −48 | 30 | 30 | 4.36 | |
L. Middle Frontal Gyrus | 8 | −46 | 26 | 42 | 4.35 | |
320 | L. Superior Frontal Gyrus | 10 | −34 | 62 | −6 | 4.68 |
L. Superior Frontal Gyrus | 11 | −32 | 56 | −14 | 4.06 | |
L. Superior Frontal Gyrus | 11 | −32 | 48 | −16 | 3.81 | |
669 | L. Inferior Parietal Lobule | 40 | −58 | −38 | 50 | 4.54 |
L. Inferior Parietal Lobule | 40 | −44 | −46 | 38 | 4.29 | |
L. Inferior Parietal Lobule | 40 | −44 | −48 | 48 | 4.28 | |
175 | L. Thalamus | −10 | −20 | 8 | 4.52 | |
L. Thalamus | −6 | −12 | 6 | 3.55 | ||
L. Thalamus | −4 | −20 | 0 | 3.26 | ||
221 | R. Middle Frontal Gyrus | 6 | 30 | −4 | 60 | 4.21 |
R. Middle Frontal Gyrus | 6 | 30 | 8 | 62 | 4.17 | |
R. Middle Frontal Gyrus | 6 | 36 | 14 | 62 | 2.88 | |
175 | L. Extra-Nuclear | 47 | −34 | 22 | −2 | 4.18 |
L. Lentiform Nucleus | −24 | 18 | 0 | 3.42 | ||
566 | L. Cingulate Gyrus | 32 | −6 | 30 | 28 | 4.17 |
R. Medial Frontal Gyrus | 8 | 8 | 22 | 46 | 3.92 | |
L. Medial Frontal Gyrus | 8 | −4 | 32 | 38 | 3.87 | |
225 | R. Caudate | 18 | 16 | 4 | 4.04 | |
R. Insula | 13 | 36 | 20 | 2 | 3.52 | |
R. Inferior Frontal Gyrus | 47 | 36 | 28 | −4 | 3.39 | |
166 | R. Declive | 36 | −64 | −16 | 3.99 | |
R. Inferior Temporal Gyrus | 37 | 48 | −64 | −4 | 3.26 | |
R. Declive | 34 | −58 | −8 | 3.03 | ||
25 | R. Precentral Gyrus | 6 | 56 | −2 | 50 | 3.92 |
14 | R. Uncus | 28 | 18 | 2 | −30 | 3.86 |
42 | L. Medial Frontal Gyrus | 9 | −4 | 42 | 28 | 3.66 |
L. Anterior Cingulate | 0 | 38 | 22 | 3.08 | ||
L. Cerebellar Tonsil | −38 | −48 | −34 | 3.65 | ||
L. Culmen | −28 | −54 | −16 | 3.61 | ||
L. Cerebellar Tonsil | −38 | −50 | −44 | 3.46 | ||
87 | R. Nodule | 10 | −52 | −30 | 3.53 | |
R. Nodule | 2 | −54 | −30 | 3.25 | ||
R. Culmen | 0 | −60 | −22 | 3.18 | ||
30 | L. Cingulate Gyrus | 31 | −8 | −10 | 44 | 3.50 |
32 | R. Cingulate Gyrus | 31 | 14 | −22 | 42 | 3.49 |
16 | R. Postcentral Gyrus | 2 | 62 | −24 | 48 | 3.49 |
54 | R. Culmen | 26 | −40 | −22 | 3.48 | |
R. Culmen | 24 | −48 | −20 | 2.88 | ||
26 | L. Culmen | −18 | −34 | −20 | 3.46 | |
17 | L. Cerebellar Tonsil | −22 | −58 | −44 | 3.45 | |
53 | R. Tuber | 48 | −76 | −30 | 3.42 | |
19 | R. Fusiform Gyrus | 19 | 52 | −74 | −14 | 3.42 |
19 | R. Inferior Occipital Gyrus | 18 | 40 | −90 | −10 | 3.36 |
61 | L. Uvula | −6 | −74 | −32 | 3.33 | |
L. Inferior Semi-Lunar Lobule | −14 | −76 | −36 | 2.93 | ||
48 | R. Transverse Temporal Gyrus | 41 | 42 | −24 | 14 | 3.27 |
14 | L. Lentiform Nucleus | −28 | 2 | 0 | 3.27 | |
32 | L. Tuber | −34 | −64 | −30 | 3.26 | |
19 | L. Orbital Gyrus | 47 | −16 | 24 | −22 | 3.26 |
20 | L. Cuneus | 17 | −4 | −96 | 2 | 3.25 |
27 | R. Postcentral Gyrus | 3 | 32 | −30 | 62 | 3.23 |
41 | R. Middle Temporal Gyrus | 39 | 56 | −54 | 10 | 3.22 |
R. Middle Temporal Gyrus | 21 | 60 | −46 | 6 | 2.94 | |
13 | L. Precuneus | 7 | −16 | −66 | 50 | 3.22 |
13 | L. Middle Frontal Gyrus | 6 | −44 | 2 | 58 | 3.15 |
32 | R. Paracentral Lobule | 5 | 12 | −36 | 54 | 3.15 |
R. Paracentral Lobule | 5 | 16 | −32 | 48 | 3.07 | |
21 | L. Uvula | −10 | −62 | −34 | 3.14 | |
24 | R. Medial Frontal Gyrus | 6 | 2 | 2 | 58 | 3.13 |
10 | R. Culmen | 32 | −52 | −20 | 3.12 | |
47 | L. Declive | −40 | −68 | −18 | 3.11 | |
11 | R. Middle Temporal Gyrus | 21 | 58 | −30 | −4 | 3.11 |
14 | L. Middle Frontal Gyrus | 11 | −40 | 38 | −18 | 3.10 |
12 | L. Paracentral Gyrus | 6 | −8 | −30 | 52 | 3.08 |
14 | L. Culmen | −44 | −48 | −24 | 3.08 | |
13 | L. Cuneus | 18 | −16 | −94 | 10 | 3.07 |
19 | R. Inferior Frontal Gyrus | 45 | 48 | 14 | 14 | 3.05 |
33 | L. Superior Parietal Lobule | 7 | −32 | −60 | 46 | 3.04 |
L. Superior Parietal Lobule | 7 | −28 | −50 | 40 | 2.85 | |
18 | R. Middle Frontal Gyrus | 10 | 40 | 62 | 2 | 2.96 |
18 | L. Cingulate Gyrus | 24 | −10 | 4 | 48 | 2.96 |
11 | R. Cuneus | 17 | 8 | −78 | 12 | 2.96 |
12 | R. Inferior Temporal Gyrus | 20 | 50 | −16 | −36 | 2.91 |
17 | L. Fusiform Gyrus | 20 | −50 | −34 | −22 | 2.88 |
28 | R. Middle Frontal Gyrus | 10 | 46 | 48 | 18 | 2.81 |