TABLE 5.
Biomarker | Hb | SaO2 | PO2art | SpO2 | AMS-C | LLS |
---|---|---|---|---|---|---|
ADMA | 0.065/0.673 | 0.040/0.794 | 0.036/0.817 | −0.012/0.924 | −0.167/0.168 | −0.195/0.109 |
SDMA | 0.085/0.578 | −0.132/0.387 | 0.055/0.718 | −0.198/0.105 | −0.074/0.545 | −0.009/0.936 |
L-Arginine | −0.249/0.990 | 0.228/0.133 | 0.080/0.601 | 0.288/0.017 | −0.086/0.477 | −0.236/0.050 |
L-Citrulline | −0.334/0.025 | 0.271/0.072 | 0.318/0.033 | 0.122/0.323 | 0.045/0.712 | −0.023/0.853 |
L-Ornithine | −0.376/0.011 | 0.525/<0.001 | 0.377/0.011 | 0.483/<0.001 | −0.213/0.070 | −0.329/0.006 |
Arg/ADMA Ratio | −0.302/0.044 | 0.183/0.229 | 0.486/<0.001 | 0.219/0.072 | 0.070/0.566 | −0.035/0.774 |
Cit/Arg Ratio | −0.149/0.328 | 0.086/0.574 | 0.436/0.003 | −0.064/0.605 | 0.115/0.344 | 0.132/0.281 |
Orn/Arg Ratio | −0.199/0.190 | 0.449/0.002 | −0.172/0.258 | 0.368/0.002 | −0.193/0.110 | −0.210/0.083 |
Values shown are Pearson correlation coefficients/p values. *values for AMS, indicate statistical significance comparing plasma concentrations of the respective biomarkers in study participants with and without acute mountain sickness. Abbreviations: ADMA, asymmetric dimethylarginine; AMS, acute mountain sickness; AMS-C, acute mountain sickness-cerebral score; Cit/Arg ratio, L-citrulline/L-arginine ratio; Hb, blood hemoglobin concentration; LLS, lake louise score; Orn/Arg ratio, L-ornithine/L-arginine ratio; PO2art, partial oxygen pressure in arterial blood; SDMA, symmetric dimethylarginine; SaO2, arterial oxygen saturation in arterial blood gas analysis; SpO2, blood oxygen saturation in pulse oxymetry. Bold values are the significant p values.