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. 2023 Dec 12;9:61. doi: 10.1038/s41540-023-00322-4

Fig. 5. Most CD8+ T-cells in HGSOC express LAG3, a marker of T cell exhaustion.

Fig. 5

a Dot plot showing expression levels and frequency of common markers of T-cell exhaustion in the entire CD45+ cell compartment. b Circle plot of CD8+ T-cell LAG3 receptor complex and all the ligands that target it. c Analysis of enriched pathways from a DEG analysis of LAG3+ CD8 T-cells compared to LAG3- T-cells in the Mouse Genome Informatics (MGI) database. d Log-normalized expression of FGL1 in the EMT-delineated compartment of cancer cells from each tumor immune phenotype.