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. 2023 Dec 13;13:22090. doi: 10.1038/s41598-023-49216-9

Table 2.

Comparison of variables between the group with ABLs and the group without ABLs.

Non-ABL ABL p-Value
(n = 815) (n = 219)
Age, years (median, IQR) 39 (30–52) 47 (33–61)  < 0.001
Sex, n (%) 0.077
Male 476 (58.4) 143 (65.3)
Female 339 (41.6) 76 (34.7)
Comorbidities, n (%)
Hypertension 101 (12.4) 53 (24.2)  < 0.001
Diabetes mellitus 61 (7.5) 34 (15.5)  < 0.001
Cardiac disease 11 (1.3) 9 (4.3) 0.018
Current smoker, n (%) 253 (29.0) 60 (27.6) 0.765
Co-ingestion
Alcohol 304 (37.3) 74 (33.8) 0.380
Drug 202 (24.8) 37 (16.9) 0.018
Exposure type, n (%) 0.069
Accidental 231 (28.3) 48 (21.9)
Intentional 584 (71.7) 199 (78.1)
Vital signs (median, IQR)
Systolic blood pressure, mmHg 124.0 (111.0–138.0) 123.0 (108.0–139.5) 0.505
Diastolic blood pressure, mmHg 75.0 (65.0–85.0) 80.0 (68.0–91.0) 0.007
Heart rate, /min 92.0 (78.0–105.0) 98.0 (85.5–113.0)  < 0.001
Respiratory rate, /min 20.0 (18.0–20.0) 20.0 (20.0–23.0)  < 0.001
GCS score < 9 at presentation in the ED, n (%) 109 (13.4) 81 (37.2)  < 0.001
Loss of consciousness, n (%) 535 (65.6) 196 (89.5)  < 0.001
COHb at presentation in the ED, % (median, IQR) 15.6 (5.9–31.2) 17.7 (5.4–31.5) 0.420
Laboratory findings at presentation in the ED (median, IQR)
White blood cell, × 103/mm3 10.0 (7.5–13.8) 14.2 (11.4–18.4)  < 0.001
Platelet, × 103/mm3 241.0 (208.0–284.0) 236.0 (196.5–287.5) 0.285
Creatinine, mg/dL 0.8 (0.6–0.9) 1.0 (0.8–1.3)  < 0.001
Creatine kinase, U/L 122.0 (76.0–236.5) 1186.5 (201.0–5761.0)  < 0.001
C-reactive protein, mg/dL 0.3 (0.1–0.3) 1.0 (0.3–3.3)  < 0.001
Troponin-I, ng/mL 0.0 (0.0–0.1) 0.6 (0.1–2.0)  < 0.001
Arterial pH 7.4 (7.4–7.4) 7.4 (7.3–7.4) 0.174
Bicarbonate, mmol/L 24.0 (21.4–25.9) 21.0 (17.2–24.2)  < 0.001
Lactate, mmol/L 1.8 (1.0–3.3) 2.6 (1.4–5.5)  < 0.001
CO Exposure duration, hour (median, IQR) 2.8 (1.0–6.0) 9.9 (4.5–14.5)  < 0.001
Interval from last CO exposure to presentation in the ED, hour (median, IQR) 2.7 (1.3–4.6) 2.9 (1.2–5.2) 0.310
Hyperbaric oxygen therapy done, n (%) 767 (94.5) 199 (91.7) 0.179

Values are expressed as the median (interquartile range) or number (proportion). ABL, acute brain lesion; COHb, carboxyhemoglobin; CO, carbon monoxide; DNS, delayed neuropsychiatric sequelae; ED, emergency department; GCS, Glasgow coma scale; SpO2, saturation of percutaneous oxygen.