Table 3.
Univariate and multivariable logistic regression analysis for predicting ABLs on MRI.
| Univariate analysis | p-value | Multivariable analysis | p-value | |
|---|---|---|---|---|
| Crude OR (95% CI) | Adjusted OR (95% CI) | |||
| Age (years) | 1.01 (1.01–1.03) | < 0.001 | 1.02 (1.00–1.03) | 0.031 |
| Comorbidities | ||||
| Hypertension | 2.26 (1.55–3.27) | < 0.001 | 1.75 (0.96–3.16) | 0.067 |
| Diabetes mellitus | 2.27 (1.44–3.54) | < 0.001 | 1.42 (0.73–2.72) | 0.295 |
| Cardiac disease | 3.13 (1.25–7.67) | 0.012 | 0.99 (0.24–3.78) | 0.993 |
| Drug co-ingestion | 0.62 (0.41–0.90) | 0.015 | 0.91 (0.54–1.51) | 0.715 |
| CO Exposure duration (hours) | 1.14 (1.11–1.17) | < 0.001 | 1.09 (1.05–1.13) | < 0.001 |
| GCS score < 9 | 3.83 (2.72–5.38) | < 0.001 | 2.41 (1.49–3.91) | < 0.001 |
| Loss of consciousness | 4.46 (2.89–7.21) | < 0.001 | 2.68 (1.49–5.06) | 0.001 |
| Vital signs | ||||
| Diastolic blood pressure (mmHg) | 1.01 (1.00–1.02) | 0.003 | 1.01 (0.99–1.02) | 0.238 |
| Heart rate (/min) | 1.02 (1.01–1.02) | < 0.001 | 1.01 (0.99–1.02) | 0.291 |
| Respiratory rate (/min) | 1.08 (1.05–1.12) | < 0.001 | 1.01 (0.96–1.06) | 0.726 |
| Laboratory findings | ||||
| White blood cell (× 103/mm3) | 1.12 (1.09–1.15) | < 0.001 | 1.05 (1.01–1.09) | 0.017 |
| Creatinine (mg/dL) | 6.12 (4.04–9.55) | < 0.001 | 1.22 (0.71–2.09) | 0.473 |
| Creatine kinase (U/L) | 1.00 (1.00–1.00) | < 0.001 | 1.00 (1.00–1.00) | 0.057 |
| C-reactive protein (mg/dL) | 1.31 (1.23–1.41) | < 0.001 | 1.06 (0.97–1.16) | 0.198 |
| Troponin-I (ng/mL) | 1.66 (1.47–1.90) | < 0.001 | 1.22 (1.08–1.41) | 0.004 |
| Bicarbonate (mmol/L) | 0.91 (0.88–0.94) | < 0.001 | 1.02 (0.96–1.09) | 0.501 |
| Lactate (mmol/L) | 1.14 (1.09–1.19) | < 0.001 | 1.08 (0.98–1.21) | 0.134 |
Definition of abbreviations: ABL, acute brain lesion; CI, confidence interval; CO, carbon monoxide; GCS, Glasgow coma scale; MRI, magnetic resonance imaging; OR, odds ratio.