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. 2023 Nov 28;110(12):2092–2102. doi: 10.1016/j.ajhg.2023.11.002

Figure 2.

Figure 2

Phenotypic characterization and ancestry inference of the individuals

(A) Aneuploidy rate versus age. x axis: maternal age in years; y axis: blastocyst aneuploidy rate. The whiskers in the box-whisker plot span a range that is 1.5× the interquartile range (IQR).

(B and C) Ancestry inference using the PGT-A data. Principal component axes (PC1 and 2 in B, PC2 and 3 in C) were defined based on analysis of 1000 Genomes reference samples and colored according to superpopulation annotations (African [AFR], admixed American [AMR], East Asian [EAS], European [EUR], South Asian [SAS]). PGT-A samples were then projected onto these axes using a Procrustes approach with LASER.26,27