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Gαq/11 regulates STK10 expression and MARK3 activity.A, representative Western blots of MARK3 and STK10 after OMM1.3 cells were treated with 1 μM of YM-254890 over a 24-h time course (n = 3). B, representative Western blots showing the effect of siGNAQ on MARK3 and STK10 expression. C, Western blot of lysates from OMM1.3 cells treated with YM-254890 for 0 to 24 h were analyzed for phosphorylation of the endogenous MARK3 substrate, CDC25C; WCL, whole cell lysate.
