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. Author manuscript; available in PMC: 2023 Dec 13.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May 27;1865(1):158462. doi: 10.1016/j.bbalip.2019.05.006

Fig. 1.

Fig. 1.

Phospholipid acyl chain remodeling reactions in eukaryotes, as found for phosphatidylcholine (PC). PC is first deacylated by a phospholipase A1 (PLA1), A2 (PLA2), or B (PLB), yielding sn-1 lyso-PC, sn-2 lyso-PC or glycerophosphocholine (GPC), respectively. Acyltransferases (AT) may generate lyso-PC in transacylation reactions. Subsequently GPC is reacylated to sn-2 lyso-PC by glycerophosphocholine acyltransferase (GPCAT), and lyso-PC’s are reacylated by AT that use acyl-CoA’s, phospholipids (in CoA-dependent or independent reactions) or lyso-phospholipids as acyl donor.