Genetic organization of the V. cholerae vie genes. The vieSAB genes are flanked by a partially sequenced, divergently transcribed ORF designated mgtE and a partially sequenced, convergently transcribed ORF designated vcc. The sites of the transcriptional fusions in strains AC-V311, AC-V336, AC-V354, AC-V296, and AC-V232 are shown at the top. The flanking sequences used to construct in-frame deletion mutations are shown at the bottom along with the corresponding deleted regions, designated by the thin angled lines.