Fig. 3.

Hot pack treatment attenuated the physical inactivity-induced cutaneous and muscular mechanical hyperalgesia. a von Frey test and b Randall–Selitto test were performed to measure the cutaneous and muscular mechanical withdrawal thresholds from baseline (BL) to 4th week. The decrease in the cutaneous and muscular mechanical withdrawal thresholds in the PI and PI + sham groups was not seen to the same extent in the PI + hot pack group. *p < 0.05, **p < 0.01, and ***p < 0.001 vs CON group. ^# p < 0.05, ^## p < 0.01, and ^### p < 0.001 vs PI group. ^† p < 0.05, ^†† p < 0.01, and ^††† p < 0.001 vs PI + sham group