Table 1 .

Experimental data on the transmural differences in intracellular electrical and mechanical properties between the ENDO and EPI cells taken into account in the cell subtype models

	ENDO	EPI	Animal species	T, °C	Source	Target model parameter	Parameter in the Appendix
Nav protein expression	Higher	Lower	Guinea pig	4	[1]	Maximum membrane i pNa conductance	Table 6
i pNa	Higher	Lower	Dog	37	[43]
i Kr , i Ks	Lower	Higher	Guinea pig	35 ± 1	[11]	i Kr , i Ks current–voltage parameters	Table 6
i NaCa	Lower	Higher	Dog	37	[44]	Maximum i NaK, current	Table 6
			Mouse	37	[18]
DHPα1	Higher	Lower	Guinea pig	4	[3]	Membrane permeability for Ca2+ through L-type channels, maximum membrane i bCa conductance	Table 6
Ca2+ release from the SR	Lower	Higher	Guinea pig	4	[3]	Sensitivity of the binding sites of ryanodine receptors to the cytosolic Ca2+	Table 7
SERCA2	Lower	Higher	Dog	4	[38]	Rate constant of SERCA Ca2+ uptake	Table 7
			Guinea pig	4	[3]
			Human	4	[13]
Passive stiffness	Higher	Lower	Guinea pig	26–27	[9]	Scaling coefficient for passive force	Table 8
			Rat, ferret	24–27	[5]
Rate constant of Xb cycling	Lower	Higher	Guinea pig	22	[8]	Rate constant for Xb attachment, Xb attachment-detachment ratio coefficient	Table 8
			Pig	22	[7]
Ca2+ sensitivity of force	Higher	Lower	Guinea pig	22	[8]	Degree of the RU end-to-end cooperativity	Table 8