Table 2.

Biometrical analysis, adipose tissue, adipose depot mass, and biochemical and hormonal determinations in adult male and female rats raised in small and normal litters (PND60, n = 8/group)

	Litter size
	Normal litter		Small litter
	Male	Female	Male	Female
Biometrical analysis
Body weight	261.3 ± 2.81	149.5 ± 2.29	321.6 ± 6.36***	177.5 ± 1.77***
Lee index	3.06 ± 0.01	2.84 ± 0.04	3.27 ± 0.01***	3.00 ± 0.02**
Adipose tissue (g/100 g b.w.)
Retroperitoneal fat	0.61 ± 0.02	0.90 ± 0.06	1.07 ± 0.05***	1.58 ± 0.17***
Epididymal fat	0.72 ± 0.01		0.97 ± 0.03***
Ovarian fat		1.04 ± 0.07		2.06 ± 0.19***
Biochemical and hormonal determinations
Glucose (mg/dl)	105.00 ± 0.93	97.87 ± 2.40	118.00 ± 2.73**	113.20 ± 4.07**
Triglycerides (mg/dl)	135.70 ± 11.70	73.21 ± 11.55	169.80 ± 10.61*	109.30 ± 10.24*
Total cholesterol (mg/dl)	70.93 ± 3.71	70.88 ± 3.40	85.37 ± 4.12*	89.48 ± 7.84*
HDL-C (mg/dl)	4.38 ± 0.14	4.67 ± 0.29	3.32 ± 0.10***	3.69 ± 0.15**
Insulin (ng/ml)	0.52 ± 0.04	0.29 ± 0.01	0.56 ± 0.07	0.41 ± 0.04*
Leptin (ng/dl)	0.69 ± 0.10	0.70 ± 0.06	1.92 ± 0.25**	1.67 ± 0.05***

Values are the mean ± SEM (Student t-test)

*p < 0.05, **p < 0.01; ***p < 0.001 compared with the normal litter