Fig. 6.

Maxi-anion channel activation upon hypotonic (a), ischemic (b) and hypoxic (c) stresses in neonatal rat cardiomyocytes. a Mean patch currents during application of alternating pulses from 0 to ±25 mV in a cell-attached patch before and during (horizontal bar) exposure to hypotonic, ischemic or hypoxic solution. b Representative current traces of maxi-anion channels activated as in (a) and elicited by step pulses of ±25 mV (the protocol shown at the top of traces) in cell-attached or inside-out patches. Modified from Dutta et al. [2]