Stimulus |
Hypertonicity of the medium |
Depolarization of membraneb,c
|
Stretchinga,f
|
Threshold |
Less than 2× normal osmolality |
About −65 mVb,c
|
To 1.2 × normal lengthf
|
Maximal heat rate |
30 – 50 mcal.g−1. min−1 (125 − 209 mJ. g−1. min−1) |
40 mcal.g−1. min−1 c (167 mJ.g−1. min−1) |
10 − 14 mcal.g−1. min−1 f (42 − 58 mJ.g−1. min−1) |
Effect of anaerobic condition |
Reduced to 1/10 |
Reduced to 1/10c
|
Reduced to 1/2a
|
Effect of procaineg (<10 mM) |
Substantially reduced |
Suppressed completelye
|
Potentiatedf
|
Effect of ouabainh (10−1 M) |
Not affected |
Not affected |
– |
In K2SO4 (isotonic) |
Remains substantial |
– |
Remains normald,f
|