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. 2016 Jul 13;67(1):19–43. doi: 10.1007/s12576-016-0470-3

Table 1.

Comparison between Yamada, Solandt and Feng effect

Yamada effect Solandt effect Feng effect
Stimulus Hypertonicity of the medium Depolarization of membraneb,c Stretchinga,f
Threshold Less than 2× normal osmolality About −65 mVb,c To 1.2 × normal lengthf
Maximal heat rate 30 – 50 mcal.g−1. min−1 (125 − 209  mJ. g−1. min−1) 40 mcal.g−1. min−1 c (167 mJ.g−1. min−1) 10 − 14 mcal.g−1. min−1 f (42 − 58 mJ.g−1. min−1)
Effect of anaerobic condition Reduced to 1/10 Reduced to 1/10c Reduced to 1/2a
Effect of procaineg (<10 mM) Substantially reduced Suppressed completelye Potentiatedf
Effect of ouabainh (10−1 M) Not affected Not affected
In K2SO4 (isotonic) Remains substantial Remains normald,f

Yamada [41]. Headings are added on top of each column

aFeng [47]; Euler [48]

bSolandt [46]

cHill and Howarth [43]

dHowarth JV, unpublished

eNovotný et al. [50]

fClinch [49]

gBlocks voltage-gated Na channels

hInhibits the Na/K ATPase (pump) and consequently increases intracellular Ca