Fig. 5.

a Time course of channel activity recorded first in the cell-attached (c.a.) mode followed by the inside-out (i.o.) mode. After patch excision, 1 μM CaM + 3 mM ATP was applied to maintain channel activity, then DTNB (1 mM) was added, and finally H₂O₂ (1 mM) was additionally applied. b Summary of channel activity induced by CaM + ATP + DTNB (n = 5) and CaM + ATP + H₂O₂ (n = 6), normalized to the activity values obtained for conditions of CaM + ATP. Data are shown as mean ± SE. NS not significant (t test)