Fig. 1.

Outward currents elicited by depolarizing voltage pulses in a senescent AFSC. a A combination of outward rectifier and A-type currents, and current fluctuations suggestive of BK K⁺(Ca²⁺) channels. Application of 4-AP modified the time constant of inactivation, and addition of TEA reversibly inhibited the current fluctuations. b Gradual development of outward currents at different times after penetration in the whole-cell configuration (same voltage protocol as in a). c Gradual development of outward currents evidenced using voltage ramps from −120 to +80 mV at 1 and 10 min after patch rupture