Table 2.
Main types of ion currents identified in senescent and cryopreserved AFSC, numbers and percentages of cells where they were found, and mean current densities
| Current | I or outward rectifier | I A inactivatable I or component | BK-like current fluctuations | I Na | I K ir inward rectifier |
|---|---|---|---|---|---|
| Senescent AFSC (n = 18) | |||||
| Number of cells | 18 | 15 | 12 | 9 | 1 |
| % of cells | 100 | 83.33 | 66.67 | 50.00 | 5.56 |
| Mean current density (pA/pF) | 6.9 | 3.1 | 1.7 | −2.8 | −5.8 |
| SD | 8.0 | 2.7 | 1.5 | 3.0 | − |
| Cryopreserved AFSC (n = 19) | |||||
| Number of cells | 19 | 9 | 13 | 12 | 6 |
| % of cells | 100 | 47.37 | 68.42 | 63.16 | 31.58 |
| Mean current density (pA/pF) | 9.2 | 5.9 | 2.9 | −13.1 | −16.6 |
| SD | 9.1 | 8.5 | 2.4 | 23.7 | 24.9 |
Current densities were measured at +60 mV for I or, I A, and BK, at maximal peak amplitude (-10 or 0 mV) for I Na, and at −120 mV for I Kir
I or outward rectifier current, I A inactivatable (A-type) I or current, I Na voltage-dependent Na+ current, I Kir inward rectifier K+ current