Table 1.
Cardiorespiratory and cerebrovascular variables during rest, isometric exercise, post-exercise muscle ischemia, and recovery
| BL | EX | PEMI | REC | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 30 s | 60 s | 90 s | 120 s | 30 s | 60 s | 90 s | 120 s | 30 s | 60 s | 90 s | 120 s | ||
| HR (beat min−1) | 71 ± 13 | 86 ± 13* | 88 ± 12* | 92 ± 12* | 96 ± 13* | 74 ± 15 | 69 ± 13 | 69 ± 13 | 69 ± 13 | 72 ± 11 | 71 ± 12 | 68 ± 12 | 66 ± 13 |
| SBP (mmHg) | 122 ± 13 | 129 ± 17* | 139 ± 14* | 147 ± 15* | 150 ± 16* | 127 ± 12 | 133 ± 13† | 133 ± 13† | 133 ± 13† | 115 ± 12 | 119 ± 12 | 120 ± 12 | 121 ± 10 |
| DBP (mmHg) | 66 ± 10 | 71 ± 11* | 79 ± 9* | 85 ± 10* | 87 ± 10* | 66 ± 9 | 75 ± 8* | 75 ± 8* | 75 ± 8* | 57 ± 9 | 64 ± 9 | 64 ± 9 | 65 ± 9 |
| MAP (mmHg) | 86 ± 11 | 91 ± 12* | 99 ± 10* | 107 ± 11* | 109 ± 12* | 87 ± 10 | 95 ± 9* | 95 ± 9* | 95 ± 10* | 77 ± 9 | 83 ± 9 | 83 ± 10 | 84 ± 9 |
| CO (%) | 0 | 27.0 ± 10.6* | 40.9 ± 20.7* | 51.1 ± 30.6* | 60.3 ± 35.8* | 26.4 ± 26.5* | 18.0 ± 20.7† | 19.0 ± 18.9† | 17.4 ± 18.2† | 15.3 ± 16.3† | 14.7 ± 16.4† | 12.2 ± 15.6 | 9.2 ± 14.2 |
| VE (L min−1) | 9.2 ± 2.7 | 9.8 ± 3.9† | 10.9 ± 4.3† | 13.9 ± 6.2* | 13.1 ± 28* | 12.2 ± 3.4* | 11.0 ± 2.8† | 9.8 ± 2.4 | 9.6 ± 3.0 | 10.0 ± 2.4 | 10.6 ± 2.2 | 9.2 ± 2.2 | 8.8 ± 1.3 |
| PETCO2 (mmHg) | 37.4 ± 4.5 | 38.7 ± 5.4 | 39.3 ± 3.7† | 40.1 ± 5.1† | 41.2 ± 54† | 39.4 ± 4.9† | 37.3 ± 4.9 | 36.5 ± 4.7 | 36.2 ± 4.7 | 39.6 ± 3.9 | 39.2 ± 4.0 | 37.9 ± 3.9 | 37.1 ± 4.4 |
| ICA blood flow (mL min−1) | 295 ± 88 | 335 ± 96* | 348 ± 100* | 330 ± 102 | 328 ± 113 | 279 ± 81 | 289 ± 83 | 281 ± 81 | 297 ± 91 | 318 ± 112 | 322 ± 105 | 319 ± 107 | 285 ± 86 |
| ECA blood flow (mL min−1) | 115 ± 49 | 131 ± 43† | 135 ± 51† | 152 ± 54* | 171 ± 49* | 147 ± 60* | 152 ± 79† | 134 ± 70† | 135 ± 66† | 114 ± 61 | 107 ± 50 | 110 ± 46 | 106 ± 43 |
| VA blood flow (mL min−1) | 93 ± 34 | 111 ± 44* | 118 ± 46* | 118 ± 46* | 115 ± 45† | 99 ± 42 | 94 ± 35 | 95 ± 39 | 94 ± 36 | 92 ± 36 | 96 ± 35 | 92 ± 32 | 92 ± 33 |
| ICA conductance (mL min−1 mmHg−1) | 3.56 ± 1.22 | 3.84 ± 1.28 | 3.56 ± 1.01 | 3.16 ± 0.96† | 3.08 ± 1.05 | 3.26 ± 0.99 | 3.07 ± 0.88 | 2.97 ± 0.78† | 3.15 ± 0.89 | 4.24 ± 1.50† | 3.99 ± 1.45 | 3.91 ± 1.39 | 3.44 ± 1.07 |
| ECA conductance (mL min−1 mmHg−1) | 1.37 ± 0.50 | 1.48 ± 0.50 | 1.38 ± 0.49 | 1.45 ± 0.49 | 1.60 ± 0.40 | 1.71 ± 0.70* | 1.61 ± 0.79† | 1.43 ± 0.72 | 1.44 ± 0.68 | 1.52 ± 0.79 | 1.32 ± 0.60 | 1.34 ± 0.55 | 1.27 ± 0.49 |
| VA conductance (mL min−1 mmHg−1) | 1.11 ± 0.41 | 1.24 ± 0.48 | 1.21 ± 0.47 | 1.12 ± 0.42 | 1.08 ± 0.44 | 1.14 ± 0.49 | 1.00 ± 0.38† | 1.01 ± 0.42† | 1.00 ± 0.37* | 1.21 ± 0.46 | 1.16 ± 0.39 | 1.10 ± 0.35 | 1.09 ± 0.37 |
Data are mean ± SD
BL baseline rest, EX static exercise, PEMI post exercise muscle ischaemia, REC recovery, HR heart rate, SBP systolic blood pressure, DBP diastolic blood pressure, MAP mean arterial pressure, CO relative change in cardiac output from the baseline, VE minute ventilation, PETCO2 end-tidal partial pressure of CO2, ICA internal carotid artery, ECA external carotid artery, VA vertebral artery
*Different from baseline rest (P < 0.01)
†Different from baseline rest (P < 0.05)