Fig. 5.

Differential expression of miRNAs in hypothalamic neurons in response to low glucose conditions. a Expression of miR-7a (black bar) and -7b (gray bar) was significantly reduced in response to low glucose conditions of 2000, 900, 500 and 200 mg/L (*p < 0.05; **p < 0.01). b Expression of miR-29b (Black Bar) and miR-29c (gray bar) was significantly reduced in response to low  glucose  conditions of 2000, 900, 500 and 200 mg/L (*p < 0.05; **p < 0.01; ***p < 0.001). c Expression of miR-30a (black bar), -30b (gray bar), -30c (white bar) was significantly reduced in response to low glucose conditions of 2000, 900, 500 and 200 mg/L (*p < 0.05; **p < 0.01; ***p < 0.001). d Expression of miR-9 was significantly reduced in response to low glucose conditions of 2000, 900, 500 and 200 mg/L (*p < 0.01). e, f Expression of miR-378-3p and miR-873-5p was significantly reduced in response to low glucose conditions of 900, 500 and 200 mg/L (*p < 0.05; **p < 0.01; ***p < 0.001). g No significant differences were found in the expression of miR-101a-3p and miR-101b-3p under different glycemic conditions (p > 0.05)