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Effect of hypoxia on myocardial β-adrenergic receptors. β-ARs in LV preparations from SHR (closed triangles), SHR/H (open squares), SHR-mtBN (closed diamonds) and SHR-mtBN/H (open circles) were characterized by radioligand binding experiments. Shown are [3H]CGP 12177 saturation binding curves (a) and competitive binding curves (b) which were constructed using the β2-AR antagonist ICI 188.551. Data represent means (±SEM) of three separate experiments performed in triplicate
