Table 2.

Binding characteristics of β-ARs

	SHR	SHR/H	SHR-mtBN	SHR-mtBN/H
B max (fmol mg−1)	21.71 ± 0.88	25.20 ± 0.38+	24.87 ± 0.73	18.37 ± 0.46§#
K D (nM)	0.49 ± 0.10	0.58 ± 0.07	0.51 ± 0.03	0.32 ± 0.01

Data are means (±SEM) of three separate experiments performed in triplicates

B _max maximal binding capacity, K _D equilibrium dissociation constant of radioligand ([³H]CGP 12177)

⁺ p < 0.05 SHR vs. SHR/H; ^§ p < 0.05 SHR/H vs. SHR-mtBN/H rats; ^# p < 0.05 SHR-mtBN vs. SHR-mtBN/H