Fig. 2.

Anion selectivity of swelling-activated currents in MCE301 cells. a Effects of extracellular chloride ion (Cl ⁻) substitution on swelling-activated currents. Extracellular Cl⁻ was replaced with ions of iodine (I ⁻), bromine (Br ⁻), fluorine (F ⁻), and gluconate (gluconate ⁻). Alternating pulses of ±40 mV were applied from a holding potential of 0 mV. Arrowhead Zero current level. b shifts of the reversal potential of swelling-activated currents under various extracellular anion conditions. Ramp pulses from −100 to +100 mV were applied