Baroreflex response curves of integrated renal (upper diagrams) and cardiac (lower diagrams) sympathetic activities during normoxia (triangles, thin lines) and hypoxia (≈10 % O2 in N2, circles, thick lines). Left-hand diagrams irrespective of whether vagus nerves are intact or severed, hypoxia increases the gain of the renal but reduces the gain of the cardiac sympathetic baroreceptor response curve without major shifts of pressure operating points. Right-hand diagrams sino-aortic denervation, i.e., elimination of baroreceptor and peripheral chemoreceptor inputs, is followed in each sympathetic branch by complete loss of gain, but pressure operation points differ between states of normoxia and hypoxia. For details, see text. Data from Iriki et al. [25]