Fig. 2.

Metabolic phenotypes of βNUCB2 KO mice. Body weight (a) and casual blood glucose levels (b) in Cre (n = 6) and βNUCB2 KO mice (n = 7) measured once every week. c Blood glucose levels at 0, 30, 60, and 120 min of glucose tolerance test (GTT) in Cre mice (n = 5) and βNUCB2 KO mice (n = 5) fasted for 8 h (7:30–15:30). d Plasma insulin concentrations at 15 min of GTT in Cre (n = 4) and βNUCB2 KO mice (n = 4). GTT was performed after fasting for 8 h in mice aged 12 weeks. Values are mean ± SEM. *P < 0.05, **P < 0.01 between Cre and βNUCB2 KO mice