Fig. 2.

Effects of acute oral administration of mitragynine and diazepam on the number of entries into the open arms (a), the percentage of time spent on open arms (b) and the total arm entries (c) in the elevated plus maze. Animals were orally treated with Tween 20 (5 ml/kg), mitragynine (10, 20 and 40 mg/kg) or diazepam (10 mg/kg) 60 min before testing. Each bar represents mean ± SEM. n = 8. *p < 0.05, **p < 0.01 and ***p < 0.001 when compared to control group