FIG. 2.

(A) Organization of the DXR biosynthesis and self-resistance genes in the region surrounding dnrX and dpsY. The drrA and drrB resistance genes are described by Guilfoile and Hutchinson (16), and dnmZ is described by Otten et al. (32). B, BamHI; Bg, BglII (B). The DNA and deduced protein sequence of the region from panel A characterized in this paper. Only the restriction stites of interest are shown. Probable translational start and stop codons are doubly and singly underlined, respectively. The fM and asterisk indicate the probable beginning and end of the open reading frame (only the first 10 amino acids of dnmZ are shown).